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: Alzheimers Association. 2017 Alzheimers Disease Facts and Figures. Alzheimers & Dementia 13 (2017): 325373. https://www.alz.org/documents_custom/2017-facts-and-figures.pdf (https://www.alz.org/documents_custom/2017-facts-and-figures.pdf).



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: Alzheimers Disease International. World Alzheimer Report 2015. https://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf (https://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf).



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notes








1


- - (    )     .         -, ,       . (   . ,    .)




2


        DrPerlmutter.com (http://drperlmutter.com/)    YouTube DavidPerlmutterMD (https://www.youtube.com/user/DavidPerlmutterMD).




3


David Perlmutter. Why We Can and Must Focus on Preventing Alzheimers. The Daily Beast. August 22, 2013. https://www.thedailybeast.com/why-we-can-and-must-focus-on-preventing-alzheimers (https://www.thedailybeast.com/why-we-can-and-must-focus-on-preventing-alzheimers).




4


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5


Alessio Fasano, et al. Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity. Nutrients 7. 3 (2015): 15651576.




6


Maureen M. Leonard, et al. Celiac Disease and Nonceliac Gluten Sensitivity. JAMA 318. 7 (2017): 647656.




7


Michal Schnaider Beeri and Joshua Sonnen. Brain BDNF Expression as a Biomarker for Cognitive Reserve Against Alzheimers Disease Progression. Neurology 86. 8 (2016): 702703.




8


Alzheimers Association. 2017 Alzheimers Disease Facts and Figures. Alzheimers & Dementia 13 (2017): 325373, https://www.alz.org/documents_custom/2017-facts-and-figures.pdf (https://www.alz.org/documents_custom/2017-facts-and-figures.pdf).




9


Alzheimers Disease International. https://www.alz.co.uk/ (https://www.alz.co.uk/).




10


Alzheimers Disease International. World Alzheimer Report 2015. https://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf (https://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf).GrainBrain_HCtext1P.indd




11


N.Scarmeas, et al. Physical Activity, Diet, and Risk of Alzheimers Disease. JAMA 302. 6 (2009): 627637.




12


      ,      ,    .




13


Jonathan Graff-Radford. Alzheimers: Can a Mediterranean Diet Lower my Risk? The Mayo Clinics FAQ. February 2, 2018. https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/expert-answers/alzheimers-disease/faq-20058062 (https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/expert-answers/alzheimers-disease/faq-20058062).




14


Allison Aubrey. The Average American Ate (Literally) a Ton This Year. The Salt (blog), NPR. December 31, 2011. https://www.npr.org/sections/thesalt/2011/12/31/144478009/the-average-american-ate-literally-a-ton-this-year (https://www.npr.org/sections/thesalt/2011/12/31/144478009/the-average-american-ate-literally-a-ton-this-year).




15


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16


Annie L. Culver, et al. Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Womens Health Initiative. Archives of Internal Medicine 172. 2 (2012): 144152.




17


H. Cederberg, et al. Increased Risk of Diabetes with Statin Treatment Is Associated with Impaired Insulin Sensitivity and Insulin Secretion: A 6-Year Follow-Up Study of the METSIM Cohort. Diabetologia 58. 5 (2015): 11091117.




18


?sa Blomstr?m, et al. Maternal Antibodies to Dietary Antigens and Risk for Nonaffective Psychosis in Offspring. American Journal of Psychiatry 169 (2012): 625632.




19


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Q. Hu, et al. Homocysteine and Alzheimers Disease: Evidence for a Causal Link from Mendelian Randomization. Journal of Alzheimers Disease 52. 2 (2016): 747756; L. Shen and H. F. Ji. Associations Between Homocysteine, Folic Acid, Vitamin B12 and Alzheimers Disease: Insights from Meta-Analyses. Journal of Alzheimers Disease 46. 3 (2015): 777790.




23


Fei Ma, et al. Plasma Homocysteine and Serum Folate and Vitamin B12 Levels in Mild Cognitive Impairment and Alzheimers Disease: A Case-Control Study. Nutrients 9. 7 (2017): 725.




24


Eric Steen, et al. Impaired Insulin and Insulin-like Growth Factor Expression and Signaling Mechanisms in Alzheimers Disease Is This Type 3 Diabetes? Journal of Alzheimers Disease 7. 1 (2005): 6380.




25


R. O. Roberts, et al. Relative Intake of Macronutrients Impacts Risk of Mild Cognitive Impairment or Dementia. Journal of Alzheimers Disease 32. 2 (2012): 329339; R. Kandimalla, et al. Is Alzheimers Disease a Type 3 Diabetes? A Critical Appraisal. Biochimica et Biophysica Acta 1863. 5 (2017): 10781089.




26


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27


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28


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29


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30


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32


      (CDC)     .  , ,       .     .




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